HCA Data Portal
Pancreas Network

Pancreas Network

The HCA datasets below focus on the network's tissues and are potential source datasets for integrated atlases.

Project TitleSpeciesMethodAnatomical EntityDisease (Donor)Cell Count Est.
A Single-Cell Transcriptome Atlas of the Human Pancreas.

Homo sapiens

CEL-seq2

pancreas

normal

12,288

A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure
2 species

inDrop

pancreas

normal

type 2 diabetes mellitus

12,404

A human cell atlas of fetal gene expression.

Homo sapiens

sci-RNA-seq3

14 anatomical entities
normal

4,062,965

A single-cell atlas of chromatin accessibility in the human genome

Homo sapiens

sci-RNA-seq

18 anatomical entities
normal

500,000

A transcriptional cross species map of pancreatic islet cells.

Homo sapiens

10x 3' v2

pancreas

normal

50,000

Combinatorial transcription factor profiles predict mature and functional human islet α and β cells

Homo sapiens

10x 3' v2

pancreas

normal

44,953

Construction of A Human Cell Landscape by Single-cell mRNA-seq

Homo sapiens

Microwell-Seq

37 anatomical entities
normal
19 diseases

702,968

Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts

Mus musculus

10x 3' v2

pancreas

pancreatic ductal adenocarcinoma

19,784

Cryopreservation and post-thaw characterization of dissociated human islet cells

Homo sapiens

Smart-seq2

pancreas

normal

189

Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.

Homo sapiens

10x 3' v2

pancreas

normal

53,950

Generation of human islet cell type-specific identity genesets.

Homo sapiens

10x 3' v3

pancreas

normal

15,000

Multimodal mapping of the tumor and peripheral blood immune landscape in human pancreatic cancer

Homo sapiens

Visium Spatial Gene Expression

2 anatomical entities
normal

pancreatic ductal adenocarcinoma

124,898

Pseudotime Ordering of Single Human β-Cells Reveals States of Insulin Production and Unfolded Protein Response.

Homo sapiens

10x 3' v3

pancreas

normal

6,241

RNA Sequencing of Single Human Islet Cells Reveals Type 2 Diabetes Genes

Homo sapiens

Fluidigm C1-based library preparation

pancreas

normal

type 2 diabetes mellitus

1,600

Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns

Homo sapiens

Smart-seq2

pancreas

normal

2,544

Single-Cell Heterogeneity Analysis and CRISPR Screen Identify Key β-Cell-Specific Disease Genes

Homo sapiens

Drop-seq

pancreas

normal

type 2 diabetes mellitus

39,905

Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes

Homo sapiens

Smart-seq2

pancreas

normal

type 2 diabetes mellitus

3,514

Single-Cell Transcriptomics of the Human Endocrine Pancreas

Homo sapiens

Smart-seq2

pancreas

normal
2 diseases

635

Single-Nucleus and In Situ RNA–Sequencing Reveal Cell Topographies in the Human Pancreas

Homo sapiens

2 library construction methods

pancreas

normal
4 diseases

120,000

Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in type 1 diabetes.

Homo sapiens

10x 3' v2

pancreas

normal

type 1 diabetes mellitus

80,000

Single-cell sequencing unveils distinct immune microenvironments with CCR6-CCL20 crosstalk in human chronic pancreatitis

Homo sapiens

2 library construction methods

pancreas

normal
2 diseases

28,547

Single-cell transcriptomes identify human islet cell signatures and reveal cell-type–specific expression changes in type 2 diabetes

Homo sapiens

Fluidigm C1-based library preparation

pancreas

normal

type 2 diabetes mellitus

638

Single-cell transcriptomics of East-Asian pancreatic islets cells

Homo sapiens

Fluidigm C1-based library preparation

pancreas

normal

223

Single-cell transcriptomics of normal pancreas, intraductal papillary mucinous neoplasm, and pancreatic adenosquamous carcinoma reveals the heterogeneous progression of pancreatic ductal and stromal cells

Homo sapiens

SCOPE-chip

pancreas

normal
2 diseases

10,346

Single-cell transcriptomics reveals unique features of human pancreatic islet cell subtypes

Homo sapiens

Smart-seq2

pancreas

normal

44,953

Single-nucleus RNA sequencing of human pancreatic islets identifies novel gene sets and distinguishes β-cell subpopulations with dynamic transcriptome profiles.

Homo sapiens

10x 3' v3

pancreas

normal

Unspecified

Tabula Muris: Transcriptomic characterization of 20 organs and tissues from Mus musculus at single cell resolution

Mus musculus

Smart-seq2

18 anatomical entities
normal

100,605

The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans

Homo sapiens

3 library construction methods
24 anatomical entities
normal
10 diseases

481,120

Using single-nucleus RNA-sequencing to interrogate transcriptomic profiles of archived human pancreatic islets

Homo sapiens

10x 3' v2

pancreas

normal

10,000